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Molecular, Cellular & Developmental Genetics

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Molecular, Cellular & Developmental Genetics

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Featuring B.Riley Lab

Through genetic analysis of zebrafish embryos, the Bruce Riley Lab studies gene regulatory networks and cell signaling pathways required for development and regeneration of sensory hair cells and neurons of the inner ear.  They use cutting edge genetics techniques, including CRISPR-Cas9 knockouts and inducible transgenes, to misexpress genes of interest to understand how regulatory genes function.  Although humans have lost the ability to replace dead and damaged hair cells and neurons, it is hoped that identifying critical genes in zebrafish can lead to effective gene therapy or stem cell therapy to restore hearing in humans. 

SAG projection       zebrafish embryo

Learn more about research in the Riley Lab by visiting their website ( or emailing Dr. Bruce Riley (