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Jorge Cruz-Reyes

Jorge Cruz-Reyes

Associate Professor

BioBio / Room 321A
Office Phone: (979) 458-3374

Education:

  1. UNDERGRADUATE EDUCATION
  2. B.S. National University of Mexico (1987)
  3. GRADUATE EDUCATION
  4. M.S. National University of Mexico (1989)
  5. Ph.D. London School of Hygiene and Tropical Medicine (1993)
  6. Postdoc. National Institute of Medical Research, UK (1994)
  7. Postdoc. Johns Hopkins School of Medicine (1995-2001)
  8. Joined Texas A&M in 2001

Biography:

Publications

  • Cruz-Reyes, J, Mooers, BH, Abu-Adas, Z, Kumar, V, Gulati, SDEAH-RHA helicaseā€¢Znf cofactor systems in kinetoplastid RNA editing and evolutionarily distant RNA processes. RNA Dis. ;3 (2):.
    doi: 10.14800/rd.1336. PubMed PMID:27540585. PubMed Central PMC4987287.

  • Kumar, V, Madina, BR, Gulati, S, Vashisht, AA, Kanyumbu, C, Pieters, B et al.REH2C Helicase and GRBC Subcomplexes May Base Pair through mRNA and Small Guide RNA in Kinetoplastid Editosomes. J. Biol. Chem. 2016;291 (11):5753-64. 
    doi: 10.1074/jbc.M115.708164. PubMed PMID:26769962. PubMed Central PMC4786712.

  • Madina, BR, Kumar, V, Mooers, BH, Cruz-Reyes, JNative Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing. PLoS ONE. 2015;10 (4):e0123441. 
    doi: 10.1371/journal.pone.0123441. PubMed PMID:25928631. PubMed Central PMC4415780.

  • Madina, BR, Kumar, V, Metz, R, Mooers, BH, Bundschuh, R, Cruz-Reyes, J et al.Native mitochondrial RNA-binding complexes in kinetoplastid RNA editing differ in guide RNA composition. RNA. 2014;20 (7):1142-52. 
    doi: 10.1261/rna.044495.114. PubMed PMID:24865612. PubMed Central PMC4114691.

  • Madina, BR, Kuppan, G, Vashisht, AA, Liang, YH, Downey, KM, Wohlschlegel, JA et al.Guide RNA biogenesis involves a novel RNase III family endoribonuclease in Trypanosoma brucei.RNA. 2011;17 (10):1821-30. 
    doi: 10.1261/rna.2815911. PubMed PMID:21810935. PubMed Central PMC3185915.

  • Reifur, L, Yu, LE, Cruz-Reyes, J, Vanhartesvelt, M, Koslowsky, DJThe impact of mRNA structure on guide RNA targeting in kinetoplastid RNA editing. PLoS ONE. 2010;5 (8):e12235. 
    doi: 10.1371/journal.pone.0012235. PubMed PMID:20808932. PubMed Central PMC2923197.

  • Simpson, L, Aphasizhev, R, Lukes, J, Cruz-Reyes, JGuide to the nomenclature of kinetoplastid RNA editing: a proposal. Protist. 2010;161 (1):2-6. 
    doi: 10.1016/j.protis.2009.10.001. PubMed PMID:19945343. PubMed Central PMC2818556.

  • Hernandez, A, Madina, BR, Ro, K, Wohlschlegel, JA, Willard, B, Kinter, MT et al.REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA (gRNA) binding. J. Biol. Chem. 2010;285 (2):1220-8. 
    doi: 10.1074/jbc.M109.051862. PubMed PMID:19850921. PubMed Central PMC2801250.

  • Hernandez, A, Panigrahi, A, Cifuentes-Rojas, C, Sacharidou, A, Stuart, K, Cruz-Reyes, J et al.Determinants for association and guide RNA-directed endonuclease cleavage by purified RNA editing complexes from Trypanosoma brucei. J. Mol. Biol. 2008;381 (1):35-48. 
    doi: 10.1016/j.jmb.2008.05.003. PubMed PMID:18572190. PubMed Central PMC2596986.

  • Alatortsev, VS, Cruz-Reyes, J, Zhelonkina, AG, Sollner-Webb, BTrypanosoma brucei RNA editing: coupled cycles of U deletion reveal processive activity of the editing complex. Mol. Cell. Biol. 2008;28 (7):2437-45. 
    doi: 10.1128/MCB.01886-07. PubMed PMID:18227152. PubMed Central PMC2268434.