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GENE Course Descriptions


GENE 603. Genetics. (4-0). Credit 4.

Development of fundamental concepts related to the structure, function, organization, transmission and distribution of genetic material. Prerequisite: GENE 301.
Offered in Fall 2015 (Instructor: Clint Magill)

GENE 606. Quantitative Phylogenetics. (2-3). Credit 3.

Designed to provide students with the theory and tools required for inference of phylogenetic (evolutionary) relationships among biological taxa using various types of comparative data including morphological characters, biochemical and molecular characters, and DNA sequences; hands-on analysis of data using contemporary tools. Prerequisite: Entomology 601 or approval of instructor. Cross-listed with ENTO 606 and WFSC 646.
Offered in Spring 2014 (Instructors: Mariana Mateos and James Woolley)

GENE 608. Critical Analysis of the Genetics Literature. Credit 1.

An introduction to primary literature in genetics provides an appreciation of how genetics can be used to address important biological questions, and experience in critically evaluating scientific papers. For first-year Genetics graduate students. Prerequisite: approval of instructor.

Offered in Fall 2015 (Instructor: Hubert Amrein)

BIOL 611. Developmental Genetics. (3-0). Credit 3

Cellular, molecular and genetic mechanisms of embryonic development revealed through genetic studies in model organisms including zebrafish, mouse, Drosophila, C. elegans, and Arapidopsis. Evolution of developmental mechanisms (Evo-Devo) is also discussed. Cross-listed with NRSC 611.
Offered in Fall 2015 (Instructors: Bruce Riley and James Erickson)

GENE 612. Population Genetics. (3-0). Credit 3.

Biological approach to genetic characteristics of populations dealing with genetic equilibrium, allelic variation, determination of genetic variation in populations, effects of mating systems, selection, mutation and drift on population parameters. Prerequisites: GENE 603; STAT 651.
Offered in Fall 2015 (Instructor: Charles Criscione)

GENE 613. Quantitative Genetics I. (3-0). Credit 3.

Quantitative genetics concepts particularly dealing with partitioning of phenotypic variance into genetic and environmental components, selection response, effects of systems of mating, genetic covariance and threshold effects. Prerequisites: GENE 612; STAT 652.

Next offered in Spring 2016 (Instructor: David Riley)

GENE 614. Maximum Likelihood Estimation of Genetic Parameters. (3-0). Credit 3.

Theoretical and analytical approaches to the application of maximum likelihood for the estimation of parameters under linear and nonlinear models; single and polygene genetic models including Hardy-Weinberg equilibrium, linkage analysis and quantitative trait loci detection. Prerequisites: GENE 603; STAT 651; STAT 652 or 601. Cross-listed with ANSC 614.
Next offered in Spring 2017 (Instructor: Clare Gill)

GENE 620. Cytogenetics. (3-0). Credit 3.

Examination and analysis of variation in chromosome structure, behavior and number; developmental and evolutionary effects of this variation. Prerequisite: GENE 603.

Next offered in Spring 2016 (Instructors: David Stelly and Terje Raudsepp)

ANSC 624. Mammalian Developmental Genetics. (3-0). Credit 3.

Genetic control of developmental pathways responsible for pattern formation and morphogenesis in mammals; genetic networks and genome organization; significance of genetic regulatory networks.  Prerequisite: GENE 301 or GENE 320; BICH 410/411 or equivalent.  Course Goal: Students will gain an understanding of genetic signal transduction pathways and regulatory networks critical for mammalian developmental processes.
Next offered in Fall 2016 (Instructor: Penny Riggs)

GENE 626. Analyses of Gene Expression. (1-3). Credit 2.

Proficiency in handling DNA and RNA gained during exercises used routinely in analyses of gene expression; RNA preparation and analysis on Northern blots; in vitro transcription and polyacrylamide gel analysis of nucleic acids; sub-cloning and mRNA quantitation using polymerase chain reaction. Prerequisites: GENE 450 or approval of instructor; radiation safety training. Cross-listed with ANSC 626.

GENE 629. Applied Animal Genomics. (3-0). Credit 3.

Theory and application of genomics by livestock industries; consideration of genetic markers, gene mapping methods, genome analysis and emerging technologies such as microarrays, transgenesis, cloning and marker assisted selection; exposure to bioinformatics tools for genomics. Prerequisite: GENE 603. Cross-listed with ANSC 629 and POSC 630.
Offered in Fall 2015 (Instructor: Clare Gill)

GENE 631. Biochemical Genetics. (3-0). Credit 3.

Genetic control of cellular metabolism. Mechanism of gene action; gene-enzyme relationships; regulation of gene expression; structure and organization of genomes; biochemical manipulation and characterization of genetic molecules. Prerequisite: GENE 431 or BICH 431; BICH 603. Cross-listed with BICH 631.

Next offered in Spring 2016 (Instructor: Ping He)

GENE 633. Conservation Genetics. (3-0). Credit 3.

Genetic concepts and techniques relevant to management and conservation of biological diversity; research and conservation within a conservation genetics framework. Prerequisites: Introductory courses in genetics and ecology or biological conservation. Cross-listed with WFSC 633.

GENE 638. Prediction of Genetic Merit. (3-0). Credit 3.

Mixed linear models and best linear unbiased prediction for genetic evaluation. Prerequisite: GENE 613. Cross-listed with ANSC 638.
Next offered in Fall 2016 (Instructor: David Riley)

GENE 643. Quantitative Genetics and Plant Breeding. (3-0). Credit 3.

Applied aspects of quantitative genetics in plant breeding; examination of methodologies to analyze quantitative variation in crop species; genetic phenomena (inbreeding heterosis and epistasis); quantitative trait loci (QTL) mapping and marker-assisted selection (MAS); genotype by environment interaction, heritability, multiple traits and selection theory with implication in plant breeding. Prerequisites: GENE 613; AGRO 641; STAT 619 and 652. Cross-listed with AGRO 643.

GENE 648. Molecular Evolution. (2-2). Credits 3.

Theory and tools used in the analysis of molecular evolutionary patterns of DNA and protein sequences. Prerequisites: Basic courses in Genetics and in Evolution. Cross-listed with WFSC 648.

GENE 654. Analysis of Complex Genomes. (3-0). Credit 3.

History and current status of genetic and molecular analysis of higher eukaryotic genomes; coverage of techniques for dissection of genomes into manageable parts; investigations in genetics, breeding and evolution; emphasis on quantitative inheritance, genetic mapping, physical mapping, map-based cloning, with examples drawn from a wide range of organisms. Prerequisite: GENE 603. Cross-listed with AGRO 654 and MEPS 654.

Next offered in Spring 2016 (Instructor: Hongbin Zhang)

GENE 655. Analysis of Complex Genomes--Lab. (0-7). Credit 3.

Laboratory methods in molecular genetic techniques for genetic mapping, physical mapping, and map-based cloning of both qualitative and quantitative phentoypes. Prerequisites: Concurrent registration in GENE 654 and approval of instructor. Cross-listed with AGRO 655 and MEPS 655.

Next offered in Spring 2016 (Instructor: Hongbin Zhang)

GENE 662. Eukaryotic Transcription. (1-0). Credit 1.

Intensive short course in molecular mechanisms of eukaryotic transcription and its regulation. Prerequisite: GENE 631 or BICH 631 or approval of instructor. Cross-listed with BICH 662.

GENE 673. Gene Expression. (1-0). Credit 1.

Oral presentations and discussions related to the biochemistry and molecular biology of gene expression in animal, plant, and microbial systems. Course may be repeated for credit up to 12 times. To be taken on a satisfactory/unsatisfactory basis. Prerequisite: Graduate classification in biochemistry or genetics or approval of instructor. Cross-listed with BICH 673.

Offered in Spring 2015 (Instructor: David Peterson)

GENE 677. Genes and Diseases. (3-0). Credit 3.

Molecular and genetic basis for human disease; structure, function and evolution of chromosomes; epigenetics; gene mapping; complex genetic traits; cancer genetics; neurodegenerative disorders; animal models (yeast, mouse, worms, fruit flies); ethics. Prerequisite: GENE 603, GENE 631, or MSCI 601 or approval of instructor. Cross-listed with MCMD 677.

GENE 681. Seminar. (1-0). Credit 1.

Reports and discussions of topics of current importance in genetics; reports to be prepared and presented by graduate students enrolled in course.
Offered in Fall 2015 (Instructor: Penny Riggs)

GENE 685. Directed Studies. Credit 1 to 4 each semester.

Individual problems or research not pertaining to thesis or dissertation. Prerequisite: Approval of instructor.

GENE 689. Special Topics in... Credit 1 to 4.

Selected topics in an identified area of genetics. May be repeated for credit. Prerequisite: Approval of instructor.

GENE 691. Research. Credit 1 or more each semester.

Prerequisite: GENE 603.

GENE 697. Teaching Genetics Labs. (1-0). Credit 1.

Theory and practical aspects of teaching genetics labs, with emphasis on content, grading, instructional methods and practical aspects of genetics labs. May be repeated for credit. Prerequisites: Graduate classification in genetics; appointment as a TA for genetics labs.
Offered in Fall 2015 and Spring 2016 (Instructor: John Ellison)


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